企业概况

Company Profile

核心业务布局

Core Business Layouts

全生命周期神经系统健康维护

全生命周期神经系统健康维护和疾病干预

Whole-life Cycle Neurological Health Maintenance & Disease Intervention

覆盖婴幼儿脑发育障碍、自闭症、多动症,青少年焦虑、抑郁等情感障碍,成年人焦虑、抑郁及认知下降,以及老年抑郁、痴呆、帕金森病等疾病。

To cover developmental disorders of infantile brains, autism spectrum disorder, ADHD, adolescent emotional disorders, adult cognitive decline, as well as elderly depression, dementia, Parkinson's disease and other diseases.

干预继发性认知与精神障碍

干预继发性认知与精神障碍

Intervention for Secondary Cognitive & Mental Disorders

针对免疫、躯体和代谢性疾病继发产生的认知损伤、精神异常等并发症,开展专业干预与调理服务。

Provide professional intervention and regulation for cognitive impairment and mental abnormalities caused by immune, physical and metabolic diseases.

AI辅助海洋药物研发

AI辅助海洋药物研发

AI-assisted Marine Drug R&D

运用人工智能技术,提升海洋活性物质筛选、作用机制研究和产品开发整体效率,搭建智能化研发体系。

To adopt artificial intelligent technology to improve the efficiency of marine active substance, mechanistic study and product development, and build an intelligent R&D system.

前沿技术平台

Advanced Technology Platform

脑疾病的细胞、动物模型

脑疾病的细胞、动物模型

Animal & Cellular Models of Brain Diseases

搭建标准化精神神经疾病的细胞、动物模式研究平台,用于药效、毒理与发病机制的验证。

Standardized cellular and animal platforms for studying efficacy, toxicity and pathogenesis verification of neuropsychiatric disorders.

人干细胞分化类脑模型

人干细胞分化类脑模型

Human Stem Cell-Derived Brain Organoid Models

干细胞体外分化构建类脑器官,高度模拟人脑生理结构,实现人体同源药物筛选。

To build up brain organoids by differentiated stem cells, which highly simulate the physiological structure of the human brain and realize human homologous medicine screenings.‌

斑马鱼疾病模拟中心

斑马鱼疾病模拟中心

A Screening Center‌ of Zebrafish Models of Human Brain Disease.

高通量斑马鱼精神神经疾病筛选体系,快速评估天然产物对儿童神经遗传发育障碍、青少年及成人情感、睡眠障碍,老年认知损伤等精神障碍的干预效果。

A high-throughput zebrafish screening system to rapidly evaluate interventions for neurodevelopmental genetic disorders in children, emotional and sleep disorders in adolescents and adults, and cognitive impairment in the elderly, as well as other related psychiatric disorders.

多组学分析及AI研发系统

多组学分析及AI研发系统

Multi-omics Analysis & AI R&D System

整合基因组学、代谢组学数据,AI智能预测活性分子,大幅缩短创新功能产品研发周期。

Integrating genomics, metabolomics and multi-omics data, the system intelligently predicts active molecules via AI, which greatly shortens the R&D cycle of innovative functional products.‌

产品优势

Product Advantages

恒海脑健康软胶囊产品实拍

把预防提前到每一天,把治疗留给晚期

Shift prevention to every single day, reserve treatment for advanced stages.

01

精神神经免疫学35年原创发现

Original Discovery of Psychoneuroimmunology in the past 35 years

世界前沿方向,非传统研发路径

World-leading frontier directions, non-traditional R&D pathways.

02

全生命周期早期脑疾病干预体系

Early Intervention of brain diseases in Whole-Life Cycle

在神经元大规模死亡前维护脑稳态

Maintain brain homeostasis before massive neuronal death occurs

03

药食同源

Homology of medicine and food.

无毒、副作用

Non-toxic, no side effects

明星产品

Star product

anlan

安澜

Anlan

  • 核心功效:改善睡眠
  • Core Efficacy: Improve Sleep
  • 适用人群:失眠人群
  • For: sleep disorders
  • 产品特点:平定神经波澜,还内心一片宁静
  • Features: ‌Calm the neural disturbance, restore inner serenity
hzm

海智明

Haizhiming

  • 核心功效:改善记忆和认知障碍
  • Core Efficacy‌: Improve memory and cognitive impairment
  • 适用人群:中老年人群、早期老年痴呆病人
  • For: Middle-aged and elderly populations, Alzheimer's disease patients at early stage
  • 产品特点:温和调理、无依赖性、草本海洋结合
  • Features‌: Gentle conditioning, non-addictive, integrated herbal and marine ingredients
海郁欣

海郁欣

Haiyuxin

  • 核心功效:改善抑郁、焦虑情绪
  • Core Efficacy‌: Relieve anxiety and depression
  • 适用人群:职场人群、情绪焦虑、抑郁人群
  • For: Working professionals, people with emotional anxiety and depression
  • 产品特点:萃取海洋生物活性成分,科学配比更高效
  • Features‌: Extracted marine bioactive components with more efficient scientifical formulations

产品管线布局

Product Pipelines

已已开发管线

DevDeveloped Pipeline

儿童多动症
ADHD
抑郁症
Depression
焦虑症
Anxiety Disorder
睡眠障碍
Sleep Disorder
老年痴呆
Alzhermer’s Disease
继发性认知功能损伤
Secondary Cognitive Impairment

待待开发管线

WaitDeveloped Pipelines

帕金森
Parkinson's Disease
精神分裂症
Schizophrenia
双向情感障碍
Bipolar Disorder
物质成瘾
Substance Addiction
脑瘫
Cerebral Palsy
智力发育迟缓
Intellectual Developmental Delay
厌学
School Aversion
茧居
Hikikomori
自闭症
Autism Spectrum Disorder

顶尖的科研平台

Leading research platforms

海洋生物药物库配图

一、合成生物学的应用

1.Efficient Development of Bioreactors

1

生物反应器的高效开发

Efficient development of South China Sea biological resources

2

原产料的生产与提纯

Production and Purification of Raw Materials

3

产学研转化应用

Industry-University-Research Transformation and Applicatio

二、斑马鱼模型在精神疾病研究与药物评估中的应用

2. Zebrafish Model for Psychiatric Research & Drug Evaluation

1

疾病模型的精准构建

Precise construction of disease models

2

高通量药物筛选平台

High-throughput drug screening platform

3

跨物种机制验证

Cross-species mechanism verification

斑马鱼实验模型配图
人源类脑器官实验配图

三、构建并优化干细胞诱导分化类脑器官的调控体系

3. Construction & Optimization of regulatory system for stem cell-induced differentiation of brain organoids

1

利用人干细胞分化人类脑,创立神经精神疾病模型更接近人类的生理和病理

By using differentiated human stem cells to build models closer to human physiology & pathology of psychiatric and neurodegenerative diseases

2

高通量海洋活性物质筛选、精准靶向药物评估与毒性预测

High-throughput screened marine active substances, to targeted drug evaluation & toxicity prediction

3

个性化保健品配方设计功能验证、动态调控以及深入研究其对类脑器官发育和功能的作用

To personally design health product formula, verify function & dynamic regulation and in-depth study their effect on brain organoid development and function

四、AI技术的应用

4. Application of AI Technology

1

相关靶点的识别:利用AI技术分析大量的生物学数据,包括基因组学和蛋白质组学数据,以识别与疾病相关的靶点。

Relevant targets of identifications: To utilize AI technique analyze massive biological data including genomics and proteomics data and identify disease-related targets.

2

结构-活性关系(SAR)建模:利用AI模型识别化合物的化学结构与其生物活性之间的关系,帮助优化药物候选物,设计出具有理想特性的新分子。

To set up structure-activity Relationship (SAR) : Using AI models to establish the correlation between compound chemical structure and biological activity, and assist optimization of drug candidates and designation of new molecules with ideal properties.

AI药物研发配图

研发成果

R&D Achievements

    已发表SCI研究论文250篇,包括与产品相关SCI论文40篇(世界顶尖科学杂志影响因子4~34.5)

    Published 250 SCI papers,including more than 40 product-related SCI papers Impact Factor (IF) of world top scientific journals ranges from 4 to 34.7

    产品已获批10项专利

    10 invention patents have been approved for products

    荣获国家级、省部级奖项 2项

    Honored 2 national and provincial Science and Technology Award

0 篇 Papers
0 项 Patents
0 项 Awards

战略合作机构

Strategic Cooperation Institutions

国外高校

Overseas Universities

联合培养人才 / 项目合作
Joint Talent Training & Project Collaboration
荷兰马斯特里赫特大学(Maastricht University)
Maastricht University, Netherlands
芬兰赫尔辛基大学(University of Helsinki)
University of Helsinki, Finland
加拿大达尔豪斯大学(Dalhousie University)
Dalhousie University, Canada
澳大利亚卧龙岗大学(University of Wollongong)
University of Wollongong, Australia
德国Ulm大学
Ulm University, Germany

合作大学和医院

Cooperative Universities & Hospitals

项目合作 / 临床实验 / 联合培养人才
Project Collaboration, Clinical Trials & Joint Talent Training
广东海洋大学
Guangdong Ocean University
广东医科大学附属医院
The Affiliated Hospital of Guangdong Medical University
河南新乡医学院附属医院
The Affiliated Hospital of Xinxiang Medical University
北京大学第六医院
Peking University Sixth Hospital
广州医科大学附属惠爱脑科医院
The Affiliated Brain Hospital of Guangzhou Medical University
南方医科大学东莞精神卫生中心
Dongguan Mental Health Center, Southern Medical University

合作企业

Cooperative en-textterprises

项目合作 / 成果转化
Project Collaboration & Achievement Transformation
脂谱生物科技(上海)有限公司
Lipid Spectrum Biotechnology (Shanghai) Co., Ltd.
山东圣州海洋生物科技有限公司
Shandong Shengzhou Marine Biotechnology Co., Ltd.

创始人

Founders

宋采教授
宋采 教授
Prof. Song Cai
创始人 / 首席科学家 / 法人
Founder / Chief Scientist / Legal Representative
爱尔兰国立大学博士,加拿大MCGill大学博士后
Ph.D. from National University of Ireland, Postdoc at McGill University
加拿大精神神经免疫学首席科学家
Canada Research Chair in Psychoneuroimmunology
精神神经免疫学创立者之一
One of the pioneers of Psychoneuroimmunology
2022–2025年 全球2%顶尖科学家
Top 2% World Scientists (2022–2025)
终身科学影响力科学家(在中国精神病研究者排名第4)
Lifetime Scientific Impact Scientist (Ranked 4th among Chinese Psychiatric Researchers)
2019–2025年中国高被引学者
Highly Cited Chinese Researcher (2019–2025)
中国海洋科学技术二等奖
Second Prize of China Marine Science and Technology
2025年中国十大杰出女科技工作者
Top 10 Chinese Outstanding Female Scientists , 2025
深圳国家级领军人才
National Leading Scientist of Shenzhen
广东海大海洋药物研究所所长
Director, Marine Drug Research Institute, Guangdong Ocean University
华大脑科学首席科学家
Chief Scientist, Huada Brain Science
多年与辉瑞,Johnson,Amarin,UpJohn研发新药
Long-term new drug R&D cooperation with Pfizer, Johnson, Amarin, UpJohn
国际期刊发表学术论文200篇,专利10项
200 academic papers published in international journals, 10 patents
李西教授
李西 博士
Dr. Li Xi
联合创始人 / 首席执行官
Co-founder / CEO
中国科学院博士 康奈尔大学医学院博士后
Ph.D. from Chinese Academy of Sciences, Postdoc at Weill Cornell Medical College of Cornell University
曾任上市集团精神卫生研究所副所长、临床研究中心主任
Former Director of Clinical Research Center, Vice Director of the Institute of Mental Health of the Listed Group‌
发表高水平SCI论文41篇,申请发明专利7项
published 41 high-level SCI papers, 7 patents
获省部级科技进步二等奖、创新创业大赛优胜奖等
Second Class of Provincial Science and Technology Progress Award Merit Award of Innovation and Entrepreneurship Competition, etc
张永平教授
张永平 教授
Prof. Zhang Yongping
联合创始人 / 研发总监
Co-founder / R&D Director
加拿大Dalhousie大学博士
Ph.D from Dalhousie of Canada
长期从事精神神经退行性疾病相关机制研究及其化学及海洋药物防治的研发工作
He has been long-term engaged in researches on the mechanisms underlying neuropsychiatric disorders and neurodegenerative diseases, as well as their prevention and treatment with chemical and marine drugs
已证明天然抗炎因子预防和改善焦虑、抑郁和AD的作用机制 以及不饱和脂肪酸不同比例组合和不同类型组合对精神疾病和神经退行性疾病的差异调节功能及针对不同病理特征的最优比例组合
He has elucidated the mechanisms of natural anti-inflammatory factors in preventing and ameliorating anxiety, depression and Alzheimer's disease (AD), as well as the differential regulatory effects of different ratio combinations and different type combinations of unsaturated fatty acids on psychiatric disorders and neurodegenerative diseases, and the optimal ratio combinations targeting different pathological features
发表高水平论文20余篇,专利10余项
He has published over 20 high-impact academic papers, over 10 patents authorized

专家顾问

Expert Consultant

Alan Kaluev院士
Alan Kaluev 院士
Alan Kaluev Academician

欧洲科学院院士,拥有俄罗斯科学院教授头衔; 俄罗斯政府“促进科学和教育”奖章(2022年); 俄罗斯各学科 前50名科学家之一; 高被引学者(按 Elsevier 学术排名); 斑马鱼领域全球前 0.03%(第10名)学者; 药学领域前 0.05%(按 ScholarGPS 学术排名); 俄罗斯“被引用次数最多”的神经科学家第一名(2022-2024年); 斯坦福大学 2023-2024 年学术排名列为全球前 2% 的科学家之一; 长期从事各种脑疾病动物模型的机制和研发。

Member of the European Academy of Sciences and Professor of the Russian Academy of Sciences. Recipient of the Russian Government Medal "For the Advancement of Science and Education" (2022). Ranked among the Top 50 Scientists across all disciplines in Russia. Highly Cited Researcher (per Elsevier rankings). Ranked in the top 0.03% worldwide (10th) in the field of zebrafish research. Ranked in the top 0.05% in pharmaceutical research (per ScholarGPS rankings). Ranked the No.1 Most-Cited Neuroscientistthe No.1 Most-Cited Neuroscientist in Russia (2022–2024). Listed among the Top 2% Scientists the Top 2% Scientists Worldwide by Stanford University (2023–2024). He has long been engaged in research on the mechanisms and development of animal models for various brain diseases.

张丹院士
张丹 院士
Zhang Dan Academician

俄罗斯国家工程院外籍院士; 美国昆泰跨国公司第一任大中国区董事长; 昆翎医药发展有限公司创始人兼CSO; 担任百华协会(Bayhelix)董事; 曾任美国华人生物医药科技协会会长; 美中药协执行董事; “千人计划”专家联谊会秘书长; 中国医药创新促进会药物研发专业委员会主任委员(第一届) 同时任国家“十一五“,”十二五”及“十三五”重大新药创制计划评审专家, 并参与国家食品药品监督管理总局药审中心的技术指南制订,新药临床评审及药审人员培训工作。

Foreign Member of the Russian Academy of Engineering Former First Chairman of Greater China Region at Quintiles Transnational Founder & CSO of Clinchoice (Tianjin) Pharmaceutical Development Co., Ltd. Serves as a Director of Bayhelix. Former President of Chinese Biopharmaceutical Association, USA (CBA). Executive Director of Sino-American Pharmaceutical Professionals Association (SAPA). Secretary of the Expert Association underthe "Thousand Talents Plan" . Chairman of the Drug Research and Development Committee (1st Session), China Pharmaceutical Innovation and Research Development Association. He also served as a review expert for the National Major New Drug Creation Program during the Eleventh, Twelfth and Thirteenth Five-Year Plans. He participated in the formulation of technical guidelines, clinical review of new drugs, and training of drug review staff at the Center for Drug Evaluation of the China Food and Drug Administration

李新民院士
李新民 院士
Li Xinmin Academician

加拿大健康科学院院士(FCAHS); 加拿大皇家医师协会执业医师(FRCPC); 萨大医学院神经精神研究所主任,终身教授; 2002 年获得 I. J. Small Indiana 杰出教授称号; 加拿大阿尔伯塔大学医学与牙科学院系主任; AHS 讲习教授和中国科研 合作项目院长特别顾问; 2018 年任助理院长; 2020 年任国际事务副院长。专注于精神病学临床和神经药理学领 域的研究,发表了近 200 篇论文,拥有 4 项发明专利,在精神病学和神经药理学领域做出了重要贡献。

Fellow of the Canadian Academy of Health Sciences(FCAHS). Licentiate of the Royal College of Physicians of Canada((FRCPC). The director of Neuroscience & Mental Health Institute, University of Saskatchewan, Tenured Professor. Awarded the title of Distinguished Professor of I. J. Small Indiana in 2002; Chair, Faculty of Medicine & Dentistry, University of Alberta. He is also an AHS Distinguished Visiting Professor & Special Advisor to the Dean for China Research Collaboration Programs. Served as Assistant Dean in 2018 and Vice Dean of International Affairs starting in 2020. His research focuses on clinical psychiatry and neuropharmacology. He has published nearly 200 papers and holds 4 invention patents, making significant contributions to the fields of psychiatry and neuropharmacology.

李文保教授
李文保 教授
Prof. Li Wenbao

曾任中国海洋大学特聘教授; 国家千人计划特聘专家; 国家海洋实验室人才卓越科学博导。 承担包括国家重大新药创制科技重大专项在内的各类纵向课题数十项,累计获批经费约1700万元。 在抗糖尿病药物开发方面的突破,被美国诺华(Novartis)药业斥资1.57亿美元收购,并进入临床实验。此外,抗肿瘤一类新药 SL01、抗肿瘤海洋I类新药MBRI-001及I类抗慢性结肠炎新药MBRI-003项目的研发均获得了国家及青岛市重大创新基金支持国家及青岛市重大创新基金支持,并进行临床前或临床中研究。

He served as a distinguished professor at the Ocean University of China; Special Invited Expert of the National Thousand Talents Plan; National Marine Laboratory Outstanding Talent Scientific Supervisor. He has undertaken dozens of vertical projects, including the National Major Science and Technology Project for New Drug Innovation, with cumulative approved funding reaching approximately 17 million yuan. The breakthrough in the development of anti-diabetic drugs was acquired by Novartis Pharmaceuticals in the U.S. for $157 million and proceeded to clinical trials. Additionally, the research and development of new Category I anti-tumor drugs SL01, new Category I marine anti-tumor drugs MBRI-001, and new Category I drugs MBRI-003 for chronic colitis were supported by the National and Qingdao Major Innovation Funds, with preclinical or clinical studies underway.

刘风鸣教授
刘风鸣 教授
Prof. Liu Fengming

曾任美国莫里尼亚生物制药公司研究员、广西药用植物研究所药用资源开发中心首席专家、北京亿利生物工程技术研究所所长、美国基尼盖茨公司CTO,国家千人计划生物医药领军人物;获国家药监局签发的新药证书、新药临床批件、医疗器械注册证25项,申请国家发明专利70余项,承担科技部中小企业创新基金2项、国家发改委国家产业化示范工程2项、参与起草1项国家行业标准,并有多项国外、国内填补空白项目。

He has served as a Professor at Morinaga Biopharmaceutical Company in the U.S., outstanding Professor of the Medicinal Resources Development Center at Guangxi Institute of Medicinal Plant Research, director of Beijing Yili Biotechnology Engineering Institute, and CTO of Genie Gates Company in the U.S. He is a leading scientist in the biopharmaceutical field under the National Thousand Talents Program. He has obtained 25 new drug certificates, clinical approval documents for new drugs, and medical device registration certificates issued by the National Medical Products Administration, applied for over 70 national invention patents, undertaken two projects under the Ministry of Science and Technology's Small and Medium Enterprise Innovation Fund, two national industrialization demonstration projects under the National Development and Reform Commission, participated in drafting one national industry standard, and led multiple projects that filled domestic and international gaps.

科研人员

Scientific Researcher

企业文化

Corporate Culture